New Possibilities for Depression: A MAP Kinase regulator

One of the problems with depression as a disorder is that the symptoms never seem to manifest the same. To give you an idea of what I’m talking about, here are some of the DSM IV recognized symptoms of depression: 1) Insomnia or hypersomnia (not sleeping OR sleeping too much) 2) Having no appetite OR […]

Read more
Depressed mice, gene therapy, and p11

Reader David sent me this paper the other day, and asked if I could blog about it. I said ok, maybe, and then I read… …”Gene therapy”… …oooooh… Sounds very cool, doesn’t it? Sounds like the FUTURE! Where’s my JETPACK!!!?!?! But of course “gene therapy” is kind of a buzzword. A lot of people throw […]

Read more
A Follow up: Depression, p21, CREB, and more

Everyone once in a while, someone sends Sci email. Often it’s silly. This one, however, was very good in that it asked for some clarification on a series of posts that I’ve been working on looking at clinical depression and possible causes and treatments, including neurogenesis in the hippocampus, cell cycle controls, and CREB. And […]

Read more
SSRIs: Talkin’ ’bout Prozac

I’m still getting a lot of questions on depression, a lot of misconceptions about how the drugs work. So I’m going to provide a little more information. And this time, you’re also getting PICTURES!

Read more